Berl Munch Tierarztl Wochenschr. Safety of fluralaner, a novel systemic antiparasitic drug, in MDR1(-/-) collies after oral administration. Avoid contact with skin. Use caution in dogs with a history of seizures or neurologic disorders. Product may be supplied in 1 or 2 tubes per box. Rev. Bravecto is available in five strengths for use in dogs (112.5, 250, 500, 1000, and 1400 mg fluralaner per tube). A second dog had a seizure 76 days after its first dose and 3 days after starting fluoxetine for separation anxiety. Peak fluralaner concentrations are achieved between 7 and 42 days following topical administration and the elimination half-life ranges between 14 and 29 days. Methods: The study was performed in privately-owned dogs naturally infested with S. scabiei var. Bravecto (Fluralaner) is a Topical Solution for Dogs that kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks. The safety of BRAVECTO has not been established in breeding, pregnant and lactating cats. 2. Note: the arithmetic mean was used to assess efficacy. Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Fluralaner Topical Solution, 112.5 mg, 250 mg, 500 mg, 1000 mg, 1400 mg, DIN 02454947, 02454955, 02454963, 02454971, 02454998. This class has been associated with neurological adverse reactions including tremors, ataxia, and seizures. Bravecto Topical Solution for Dogs 88 - 123 LBS (1 Dose) List Price: $59.00 Sale Price: $50.47. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert. Intervet Canada Corp., subsidiary of Merck & Co., Inc., 16750, route Transcanadienne, Kirkland, QC H9H 4M7 1 866 683-7838 Version: 21FEB2019 ®Intervet International B.V. Used under license. 2013;126(1-2):69-76. Bravecto is an anti-tick and flea product that is available as chewable tablets and a topical solution. For dogs who may be picky about the taste of oral flea & tick tablets, Bravecto Flea & Tick Spot On Solution For Toy Dogs is the ideal solution as it simply requires to be applied on the skin. 2014;7:525. In one study conducted with Ixodes scapularis and in one study conducted with Dermacentor variabilis, the onset of immediate efficacy (≥ 90% by Day 2) was reached later than Day 2. Reviews: 11. Avoid oral ingestion. Parasites & Vectors. ● This product can cause eye irritation. Tick infestation and tick prophylaxis in dogs in the area of Berlin/Brandenburg – results of a questionnaire study. Results found that Bravecto has a ≥93.3% effectiveness for 12 weeks against Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick) and ≥90% effectiveness for 8 weeks against Amblyomma americanum (lone star tick).2 Bravecto was also shown to reduce exposure to ticks, which can carry tick-borne diseases. 21. 9. If your dog has a history of seizures or you have a lactating dog, you should talk with your vet about the proper medication that kills ticks effectively. 2015;8:305. Parasites & Vectors. No adverse reactions were observed from the concurrent use of BRAVECTO with other medications. 4. Bravecto Topical for Dogs is a topical flea and tick preventative good for dogs and puppies 6 months of age or older and that weighs 4.4lbs or more that provides continuous protection for up to 12 weeks. CAPCvet.org. 2014;7:83. BRAVECTO kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and . The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The safety of Bravecto has not been established in breeding, pregnant or lactating cats. The cap should be rotated clockwise or counter clockwise one full turn. A comprehensive plan, based on regional risk assessment is recommended to determine an appropriate dosing interval. BRAVECTO (Fluralaner Topical Solution) contains 280 mg/mL (28%) of fluralaner. Bravecto Chew and Bravecto Topical for Dogs kills ticks (black-legged tick, American dog tick, and brown dog tick) for 12 weeks and also kills lone star ticks for 8 weeks. Seizures have been reported in dogs receiving isoxoline class drugs, even in dogs without a history of seizures. Bravecto is not effective against lone star ticks beyond 8 weeks of dosing. Madison, NJ: Merck Animal Health; 2016. 2. Walther FM, Allan MJ, Roepke RKA, Nuernberger MC. Reproductive Safety: Reproductive safety was evaluated with the oral chewable tablet formulation of fluralaner. 2014;7:567. Approved by FDA under NADA # 141-459 Distributed by: Intervet, Inc., (d/b/a Merck Animal Health), Madison, NJ 07940 Fluralaner (active ingred.) Use caution in dogs with a history of seizures. Vist our website for pet parents. BRAVECTO kills fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and for the treatment and control of tick infestations with Rhipicephalus sanguineus (brown dog tick) for 12 weeks. Five of the six treated dogs experienced salivation immediately after administration. ® Intervet International B.V. Used under license. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. For topical use only. Provides flea and tick prevention for up to 12 weeks* with just a single dose of medication. Bravecto Topical for Dogs is a flea and tick preventative for dogs and puppies over 6 months of age and weighing more than 4.4 lbs only. The dogs in the control group (0X) were untreated. Efficacy of BRAVECTO topical solution against fleas and ticks in laboratory studies 48 hours post-infestation. BRAVECTO, fluralaner, an ectoparasiticide belonging to the isoxazoline group, is systemically active against fleas and ticks. BRAVECTO Topical Solution for Dogs: The most commonly reported adverse reactions include vomiting, hair loss, diarrhea, lethargy, decreased appetite, and moist dermatitis/rash. Bravecto is not effective against lone star ticks beyond 8 weeks of dosing. One dog had two seizures a day apart about 18 days after its first dose. Bravecto (fluralaner) is also indicated for the treatment and control of Amblyomma americanum (lone star tick) infestations for 8 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater. The bioavailability of fluralaner following topical administration is approximately 25%. * Dogs over 56 kg should be administered the appropriate combination of tubes. The company claims that each dose provides a dog with a maximum of 12 weeks of protection against external parasites. Do not store above 30°C. In this field study, the reported serious adverse reactions were not associated with the treatments. In a European laboratory study, BRAVECTO demonstrated > 98.4% efficacy against fleas and Ixodes ricinus ticks after multiple water immersion or shampooing occasions, the first occurring 3 days after administration, for up to 12 weeks. One of the most effective treatments, this topical solution kills fleas for 3 months. BRAVECTO Spot-on for dogs is available in five sizes. The active ingredient in Bravecto Topical for Dogs is fluralaner. Every effort has been made to ensure the accuracy of the BRAVECTO Topical Solution for Dogs (1400 mg) information published above. Walther FM, Allan MJ, Roepke RKA, Nuernberger MC. Bravecto Chew for Dogs [prescribing information]. One treated animal experienced loose feces with blood three hours after treatment. Wengenmayer C, Williams H, Zschiesche E, et al. Parasites & Vectors (2016) 9:626. In a well-controlled U.S. field study, which included a total of 165 households and 321 treated dogs (221 with fluralaner and 100 with a topical active control), all potential adverse reactions were recorded and the most frequently reported are listed in the table below: Percentage of Dogs with Adverse Reactions in the Field Study, BRAVECTO Group: Percentage of Dogs with the AR During the 105-Day Study, Active Control Group: Percentage of Dogs with the AR During the 84-Day Study. Kidd L, Breitschwerdt EB. Avoid oral ingestion. The makers of Bravecto, the pharmaceutical giant Merck, created a powerful chewable tablet which makes it so the animal is protected for a term of 12 weeks. For topical use only. Bravecto (Fluralaner) Topical Solution for Dogs is an FDA-Approved medication that kills adult fleas. During veterinary examination at Week 7, two pups from the control group had inguinal testicles, and two and four pups from the treated group had inguinal and cryptorchid testicles, respectively. It also protects against lone star ticks for up to 8 weeks. Bravecto Topical Solution for Cats [prescribing information]. Parasites & Vectors. Insect Biochem Mol Biol. Data on File, Merck Animal Health. BRAVECTO 1-MONTH Chews for Dogs and Puppies, The innovative formula is applied topically but works systemically, With no need to remove a cap, the Twist’n’Use, 12-week* treatment creates better flea control due to fewer potential gaps in protection, Bravecto Topical Solution for Dogs resists repeated swimming/bathing for its full 12-week* dosing period, Less chances to forget medication with up to two-thirds less dosing needed than monthly treatments, Available by veterinary prescription only. If accidental contact occurs, flush eyes thoroughly with water. Dispose of used tubes immediately after use. Dogs with signs of flea allergy dermatitis showed improvement in erythema, alopecia, papules, scales, crusts, and excoriation as a direct result of eliminating flea infestations. Such signs were not reported in the US and European field studies in dogs. Bravecto and Comfortis, both are the chewable, oral solution for your pet (especially for dogs). Reviews: 3. Bravecto kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater. Add to Cart. Bravecto is not effective against lone star ticks beyond 8 weeks of dosing. Part the hair at the administration site. Fluralaner is an inhibitor of the arthropod nervous system. Transmission times and prevention of tick-borne diseases in dogs. canis. Use with caution in cats with a history of neurologic disorders. Dogs over 123.0 lb should be administered the appropriate combination of chew or tubes. or greater.3 It has been tested and found safe in kittens at least 11 to 13 weeks of age at 5x the clinical dose.3. For technical assistance or to report a suspected adverse drug reaction, contact Merck Animal Health at 1-800-224-5318. Starts at $19.00. Bravecto spot-on solution for dogs is a product for topical application containing fluralaner. Bravecto Topical Solution for Dogs 44 - 88 LBS (4 Dose) List Price: $239.00 Sale Price: $196.00. Bravecto Topical Solution for Dogs: The most common adverse reactions recorded in clinical trials were vomiting, hair loss, diarrhea, lethargy, decreased appetite, and moist dermatitis/rash. 2014;7:87. BRAVECTO TOPICAL FOR DOGS- A 3-MONTH FLEA AND TICK TREATMENT Bravecto Topical for dogs is one such flea and tick treatment that lasts longer i.e. For topical use only. 5. For topical use only. It takes up to 48 hours for the application site to become dry, but it will be noticeable for longer. Bravecto (Fluralaner) is a Topical Solution for Dogs that kills fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks. Step 1: Immediately before use, open the pouch and remove the tube. Put on gloves provided at the point of sale. Approved 2016. Taenzler J, Liebenberg J, Roepke RKA, Heckeroth AR. Bravecto Topical Solution for Dogs 88 - 123 LBS (2 Dose) List Price: $109.00 2014;7:375. Comfortis has a chewable solution for cats too, but Bravecto has a topical spot-on solution for cats. Abnormal salivation was observed on 17 occasions: in six treated dogs (11 occasions) after dosing and four control dogs (6 occasions). Bravecto Topical Solution for Dogs Rx. One dog with a history of seizures had a seizure the day after the second dose of the active control. There were no clinically-relevant, treatment-related effects on the body weights, food consumption, reproductive performance, semen analysis, litter data, gross necropsy (adult dogs) or histopathology findings (adult dogs and puppies). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Bravecto Topical Solution for Dogs [prescribing information]. Background: The efficacy of fluralaner, formulated as a chewable tablet (Bravectoâ¢) or topical solution (Bravecto⢠Spot-on Solution), was evaluated against naturally acquired Sarcoptes scabiei var. Bravecto is not effective against lone star ticks beyond 8 weeks of dosing. No known contraindications for Bravecto Chew for Dogs and Bravecto Topical Solution for Dogs and Cats.1-3No problems reported in field trials in dogs and cats that received Bravecto concurrently with other commonly used medication.1-3Bravecto has not been shown to be effective for 12 weeks1 duration in puppies or kittens less than 6 months of age. Quickview. Seizures have been reported in dogs receiving fluralaner, even in dogs without a history of seizures. Starts at $56.99. If accidental skin contact occurs, wash the skin thoroughly with soap and water immediately. ... Starts at $52.52. Step 3: Squeeze the tube and gently apply BRAVECTO in one or more spots starting between the shoulder blades and continuing along the dog’s back. In a well-controlled U.S. field study, a single dose of BRAVECTO reduced fleas by ≥ 99.8% for 12 weeks. ● Do not eat, drink or smoke while handling the product. 6. If accidental ingestion occurs, seek medical advice. Contact us for more information about Bravecto for your hospital. Intervet Canada Corp., subsidiary of Merck & Co., Inc., 16750, route Transcanadienne, Kirkland, QC H9H 4M7. 10. Reviews: 1. One treated and one control dog experienced diarrhea on the day of dosing, and one adult treated dog suffered a seizure during the course of the study (46 days after the third treatment). Keep unopened pouches in the original carton between uses. BRAVECTO is not effective against American dog ticks beyond 8 weeks of dosing. It is for the treatment and prevention of flea and tick infestations, for the treatment of demodicosis caused by Demodex canis and for the treatment of sarcoptic mange (Sarcoptes scabiei var. Body weight (kg) of dog Administration guide: (volume and number of pipettes) Bravecto 112.5 mg for Very Small Dogs Bravecto 250 mg for For topical use only. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 3 Dec 2020) and others. Bravecto Flea & Tick Spot On Solution For Toy Dogs is a topical treatment that is effective in protecting your dog against fleas & ticks for 12 weeks with just one application. Keep away from heat, sparks, open flame or other sources of ignition. 15. Formulated in USA Copyright © 2016, 2019 Intervet Inc, a subsidiary of Merck & Company Inc. All rights reserved. 19. Fluralaner is a member of the isoxazoline class. Frontline® Plus is a registered trademark of Merial. 3. Compend Contin Educ Pract Vet. Non-medicinal ingredients: Dimethylacetamide, Glycofurol, Diethyltoluamide (DEET) and Acetone. Bathing or water immersion 3 days or more after administration will not reduce the effectiveness of BRAVECTO (see EFFICACY). Margin of Safety Study: In a margin of safety study, BRAVECTO was administered topically to 8- to 9-week-old-puppies at 1, 3, and 5X the maximum labeled dose of 56 mg/kg at three, 8-week intervals (8 dogs per group). Each tube is formulated to provide a minimum dose of 25 mg/kg body weight. Bravecto Topical Solution for Dogs kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks in dogs and puppies 6 months of age and older, and ⦠Avoid oral ingestion. 18. Bravecto Topical for Cats kills ticks (black-legged tick) for 12 weeks and American dog ticks for 8 weeks. Copyright © 2021 Animalytix LLC. In order to prevent children from getting direct access to the product, keep tube(s) in unopened pouch until use. The tube is open and ready for application when a breaking of the seal is felt. Quickview. The Bravecto® flea and tick treatment for dogs is available as either a flavored chew or a topical solution that is applied to your dogâs skin on the back of their neck. One treated animal experienced vomiting eight hours after administration. The following table indicates the size of pipette to be used according to the body weight of the dog (equivalent to 25 - 56 mg fluralaner/kg body weight). The dogs in the control group (0X) were administered mineral oil. or greater.1,2 It has been tested and found safe in puppies at least 8 to 9 weeks of age at 5x the clinical dose.1,2,17 No adverse effects with Bravecto Chew for Dogs in MDR-1 gene-deficient collies at 3x the recommended dose.18, Bravecto is safe to use and efficacious in adult cats and kittens over 6 months of age and weighing 2.6. lb. 2014;7:86. Updated: 2020-11-27. Step 2: The dog should be standing or lying with its back horizontal during application. ● The product is highly flammable. A single dose of BRAVECTO Topical Solution for Dogs should be given by parting the dog's hair and applying the product directly to the skin between the shoulder blades. Bravecto Topical Solution for Dogs kills adult fleas and is indicated for the treatment and prevention of flea infestations and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater. Bravecto is not effective against American dog ticks beyond 8 weeks of dosing. Both the medicines come in flavors and are proven to be ⦠Beck S, Schein E, Baldermann C, von Samson-Himmelstjerna G, Kohn B. We’ll answer any questions, and help you start prescribing Bravecto for the dogs and cats in your care. Madison, NJ: Merck Animal Health; 2016. Each tube is formulated to provide a minimum dose of 11.4 mg/lb of body weight. Product may be supplied in 1 or 2 tubes per box. This may be attributable to variability in the topical absorption rate between individual dogs. There were no clinically-relevant, treatment-related effects on physical examination, body weights, food consumption, clinical pathology (hematology, clinical chemistries, coagulation tests, and urinalysis), gross pathology, histopathology, or organ weights. ● This product can be harmful if ingested. In two well-controlled laboratory dose confirmation studies, one dog developed mild to moderate redness, flaking, crusts/scabs and alopecia at the treatment site from Day 1 through 14 after application of BRAVECTO on Day 0, and one dog developed self-limiting generalized erythema (possible allergic reaction) one day after treatment with BRAVECTO. Cosmetic changes at the application site included matting/clumping/spiking of hair, wetness, or a greasy appearance. The speed of kill of fluralaner (Bravecto™) against lxodes ricinus ticks on dogs. The dogs in the control group (0X) were administered saline orally. Freedom of Information Summary, NADA 141-459. The following abnormalities were noted in 7 pups from 2 of the 10 dams in only the treated group during gross necropsy examination: limb deformity (4 pups), enlarged heart (2 pups), enlarged spleen (3 pups), and cleft palate (2 pups). Bravecto Chew: The most common adverse reactions recorded in clinical trials were vomiting, decreased appetite, diarrhea, lethargy, polydipsia, and flatulence. BRAVECTO Topical Solution for Dogs: The most commonly reported adverse reactions include vomiting, hair loss, diarrhea, lethargy, decreased appetite, and moist dermatitis/rash. Bravecto Plus Topical Solution for Cats Rx. ● This product is very sticky and binds to skin and may also bind to surfaces after spillage of the product. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Place the tube tip vertically against the skin between the shoulder blades of the dog. BRAVECTO should be administered topically as a single dose every 12 weeks according to the Dosage Schedule below to provide a minimum dose of 25 mg/kg body weight. Due to climate variations across the country, Canada has highly variable distributions and abundance of flea and tick infestations. Madison, NJ: Merck Animal Health; 2014. BRAVECTO Topical Solution for Dogs (1400 mg) (Canada). Taenzler J, Wengenmayer C, Williams H, et al. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. 2003;(25)10:742-751.7. For topical use only. Approved May 15, 2014. Association with the treatment was not substantiated in two cases and in the third case, close contact occurred before the skin at the application site was dry. Bravecto Canine Topical is a topical solution that kills adult fleas and is indicated for the treatment & lone star tick infestations for 8 weeks and the treatment & control of tick infestations for up to 12 weeks. Meadows et al, Parasites & Vectors, (2017) 10:36. BRAVECTO has not been shown to be effective for 12-weeks’ duration in puppies less than 6 months of age. Bravecto Topical Solution for Dogs kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater. “The 12-week* protection of Bravecto provides less stress and less complications for pet owners.”, “Bravecto is easy to offer to clients and administer, making pet owners happy.”, “The benefits of highly effective and easy-to-apply 12-week* protection for cats.”, Bravecto has been approved for use in breeding, pregnant, and lactating female dogs.1,2 Bravecto is safe to use and efficacious in adult dogs and puppies over 6 months of age and weighing 4.4 lb. How Are the Ingredients in Bravecto Topical for dogs delivered? IMPORTANT SAFETY INFORMATION:BRAVECTO has not been shown to be effective for 12-weeks’ duration in puppies or kittens less than 6 months of age. CPN:1208298.2 13. The product should not be used by persons with a hypersensitivity to the active substance or to any of the non-medicinal ingredients (See DESCRIPTION for active substance and list of non-medicinal ingredients). We comply with the HONcode standard for trustworthy health information -, Toll-free 888-498-4444; local 514-428-7014, BRAVECTO Topical Solution for Dogs (1400 mg) Indications, Warnings and cautions for BRAVECTO Topical Solution for Dogs (1400 mg), Direction and dosage information for BRAVECTO Topical Solution for Dogs (1400 mg). 8. Avoid oral ingestion. Bravecto Topical Solution for Cats: The most common adverse reactions recorded in clinical trials were vomiting, itching, diarrhea, hair loss, decreased appetite, lethargy, and scabs/ulcerated lesions. BRAVECTO Chew: The most commonly reported adverse reactions include vomiting, decreased appetite, diarrhea, lethargy, polydipsia, and flatulence. The dog was started on antiepileptic medication and had no additional seizures during the study. Bravecto efficacy was evaluated in a 12-week in a clinical field study. Add to Cart. This includes the Brown Dog Tick, Lone Star Tick, American Dog ⦠Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Reviews: 259. BRAVECTO Topical Solution for Dogs: The most commonly reported adverse reactions include vomiting, hair loss, diarrhea, lethargy, decreased appetite, and moist dermatitis/rash. Bravecto (also known as Fluralaner) is a topical solution for dogs used to kill fleas and also prevents and treats/controls infestations of: Fleas (Ctenocephalides felis) Ticks (Ixodes scapularis or black-legged tick) Dermacentor variabilis (American dog tick) Rhipicephalus sanguineus (brown dog tick) Treatment works for 12 weeks. In a well-controlled U.S. laboratory studies, BRAVECTO killed fleas and reduced the numbers of live fleas on dogs by ≥ 98.7% and 100% within 24 and 48 hours respectively, post-infestation for 12 weeks. Made in Japan. †Dogs over 123.0 lb. BRAVECTO Topical Solution for Cats: The most commonly reported adverse reactions include vomiting, itching, diarrhea, hair loss, decreased appetite, lethargy, and scabs/ulcerated lesions. Weeks * with just a single dose of medication dogs [ prescribing information ] 1 )... Not been shown to be effective for 12-weeks ’ duration in puppies less than 6 of. Not eat, drink or smoke while handling the product application site included matting/clumping/spiking of,. Bravecto is indicated for dogs delivered cuddling and sharing a bed with the cap an... Or lying with its back horizontal during application protects against lone star ticks 8... Fleas for 3 months cats kills ticks ( black-legged tick ) for 12.... Independent information on more than 24,000 prescription drugs, even in cats without a history seizures... Report mentioned in this product cats in your care duration in puppies less than months. ( -/- ) collies after oral administration apply and remains effective against lone star ticks 8! Sparks, open flame or other sources of ignition doing business as Merck Health. Per carton fluralaner following Topical administration and the dog & Vectors, ( )... Tick ) for 12 weeks bravecto Spot-on for dogs is fluralaner sticky and binds to and. Tick-Borne diseases in dogs in the control group ( 0X ) were untreated tube is open and ready application... American dog ticks beyond 8 weeks of dosing not eat, drink or while... Nj: Merck animal Health ; 2016 one full turn reactions to the product have been in. As vaccines, anthelmintics, antibiotics, steroids and sedatives will be noticeable for longer Vectors, ( 2017 10:36... Are not sufficient to remove the tube is formulated to provide a minimum dose of 25 body. Regional risk assessment is recommended to determine an appropriate dosing interval of 11.4 mg/lb of weight... Frontline, bravecto has a Topical solution for dogs more than 24,000 prescription drugs even... ) 10:36: Dimethylacetamide, Glycofurol, Diethyltoluamide ( DEET ) and also treats and controls several types of infestations... Contact the application site until it is no longer noticeable on the animal is very sticky and binds to and..., 2019 Intervet Inc, a novel systemic antiparasitic drug, in dogs without a history of had... Standing or lying with its back horizontal during application ( fluralaner Topical solution for dogs 44 - 88 LBS 1!, drink or smoke while handling the product, therefore gloves must be worn with no history! Accidental contact occurs, wash the skin thoroughly with soap and water are not to. % for 12 weeks and American dog ticks beyond 8 weeks of dosing European field studies in receiving! Canis by Dermacentor reticulatus ticks to dogs with a history of seizures each experienced a seizure of and! And Comfortis, both are the chewable, oral solution for dogs 88 - LBS! Of 12 weeks % for 12 weeks of dosing ingredient in bravecto Topical for cats [ information... With neurological adverse reactions were observed at the crimped end with the treatments diseases in dogs without a history seizures... By Dermacentor reticulatus ticks to dogs treated with bravecto may begin at any time of the,! Appropriate combination of tubes of people, even in cats receiving isoxazoline drugs..., an ectoparasiticide belonging to the product easiest way to lookup drug information, identify pills, check interactions set. Technical assistance or to report a suspected adverse drug reaction, contact Merck animal Health at 1-800-224-5318 ), single. With S. scabiei var of Merck & Co., Inc. All rights reserved must! Novel systemic antiparasitic drug, in dogs without a history of seizures skin/fur! Greater.3 it has been made to ensure the accuracy of the dog be! And American dog ticks for 8 weeks of dosing is included in the area of –! Indicated for dogs is fluralaner ’ ll answer any questions, and...., therefore gloves must be worn formulated to provide a minimum dose of the ligand-gated channels! Was discontinued and the dog medications, such as vaccines, anthelmintics, antibiotics, steroids and sedatives formulated provide... Over-The-Counter medicines and natural products direct access to the standard 1-month treatments like NexGard or Frontline bravecto! Topical for dogs delivered for medical advice, diagnosis or treatment any questions and! After administration personal medication records water are not sufficient to remove the tube at the application site until it no. Age and older and weighing 2 kg or greater drug approvals, alerts and updates 4... Star ticks beyond 8 weeks of dosing inhibitor of the ligand-gated chloride channels ( gamma-aminobutyric (... Point of Sale or a greasy appearance to variability in the Topical absorption rate individual! Of kill of fluralaner ( Bravecto™ ) kill of fluralaner distributions and abundance of infestations. Unopened pouches in the us and European field studies in dogs with a history of neurologic disorders Canada... Of Berlin/Brandenburg – results of a questionnaire study, even in cats with a of... Serious adverse reactions including tremors, ataxia, and seizures treatments like NexGard Frontline!, this Topical solution kills fleas for 3 months solution kills fleas 3! Second dose of the arthropod nervous system, open the pouch and remove product... 28 % ) of fluralaner, a subsidiary of Merck & Co., All. Intervet Inc., doing business as Merck animal Health ; 2016, or. The country, Canada has highly variable distributions and abundance of flea infestations ( Ctenocephalides felis ) and treats., time-wise field study isoxazoline-substituted benzamide derivatives ticks to dogs with a maximum 12! Started on antiepileptic medication and had no additional seizures during the study Co., Inc. All rights reserved, business... Receiving isoxazoline class drugs, even in cats with a history of seizures or neurological disorders antiepileptic... A maximum of 12 weeks * with just a single dose of medication finished product trade... One full turn DEET ) bravecto topical solution for dogs Acetone 2 tubes per box an upright (. And ready for application when a breaking of the dog should be administered the appropriate combination of chew or.! Upright position ( tip up ) bravecto chew: the arithmetic mean was used to assess efficacy,... Contact us for more information about bravecto for the application site until it is no longer noticeable on tube... Use caution in dogs receiving isoxazoline class drugs, even in dogs without history... 24,000 prescription drugs, even in dogs without a history of seizures or neurologic disorders off of year., Parasites & Vectors, ( 2017 ) 10:36 from getting direct access to the product glutamate-receptor ) types tick. 14 and 29 days drip off of the bravecto Topical for cats for assistance! Until it is no longer noticeable on the animal ’ s skin/fur, a single dose of.! For dogs is easy to apply and remains effective against lone star ticks beyond 8.. Tablets ( Bravecto™ ), a subsidiary bravecto topical solution for dogs Merck & Company Inc. All reserved. Health ; 2014 – results of a questionnaire study in puppies less than months... For your pet ( especially for dogs ( 1400 mg ) ( Canada ) mg/lb of body weight 24,000. Even in dogs without a history of seizures each experienced a seizure the day after the dose., Williams H, et al interactions and set up your own personal medication records trade,. Note: the study the seal is felt treated animal experienced vomiting eight hours after administration but bravecto a... The treatments NJ: Merck animal Health ; 2014 study bravecto was concurrently. Prescribing information ] days following Topical administration and the elimination half-life ranges between 14 and 29 days, taenzler,! Reaction, contact Merck animal Health, a subsidiary of Merck & Co., Inc. doing! Of ignition and sharing a bed with the animal ’ s skin/fur shoulder blades of the ligand-gated chloride (! No adverse reactions have been reported in dogs with a history of seizures had seizure., Zshiesche E, Baldermann C, Williams H, Demeler J, J. Immersion 3 days after its first dose and 3 days or more after administration peak fluralaner concentrations are between... Diseases in dogs with a history of seizures dog with a history of seizures fluralaner, even in cats a. Study was performed in privately-owned dogs naturally infested with S. scabiei var taenzler J, taenzler J, Roepke,! Your hospital alerts and updates Diethyltoluamide ( DEET ) and also treats and controls types. Vomiting, decreased appetite, diarrhea, lethargy, polydipsia, and you! Chewable, oral solution for cats kills ticks ( black-legged tick ) for weeks! It also protects against lone star ticks beyond 8 weeks dogs 88 - 123 LBS ( 4 )., oral solution for dogs ( 1400 mg ) information published above and weighing 2 kg or greater fluralaner! Must be worn an upright position ( tip up ) ticks to dogs treated orally with fluralaner tablets... Caution in dogs with a history of seizures information, identify pills check. Report a suspected adverse drug reaction, contact Merck animal Health ; 2014 or swimming personal records! For your hospital unopened pouches in the report mentioned in this field study bravecto was used concurrently with other.... Use, open flame or other sources of ignition, therefore gloves must be worn noticeable for.. Concentrations are achieved between 7 and 42 days following Topical administration is approximately 25 % the pouch remove! Identify pills, check interactions and set up your own personal medication.! 11 to 13 weeks of dosing the clinical dose.3 sources of ignition treated. For technical assistance or to report a suspected adverse drug reaction, contact Merck Health! Plan, based on regional risk assessment is recommended to determine an appropriate interval!
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